microRNA a macro Revolution in Medical Biotechnologies
Keywords:
RNAi, medical biotechnologies, silencing genesAbstract
Over the past decade RNA interference mechanism has emerged as a natural pathway for
silencing gene expression. Starting with the field of plant biotechnology in early 90s, our knowledge
about RNAi proved presently its enormous potential for engineering the control of gene expression,
as well as for its use as a tool in functional genomics. The predominantly practical significance of
RNAi is conferred by its application as a therapeutic mechanism. RNAi may yield RNA based drugs
to treat human diseases and it proved to be efficient in control of some parasites interaction with
their host genome.
This article is based on a review of the literature referring to RNA from the PubMed database.