Studies on Obtaining a Probiotic Product Based on Mixed Microbian Biomass

Abstract

Biotechnological studies on obtaining the probiotic product consist in the growth of the 3 microorganism strains in the specific micropilot conditions, followed by the separation of the respective biomasses in the broth, the drying of the biomass of Saccharomyces cerevisiae, Lactobacillus acidophilus and Bacillus subtilis.  Pharmaceutical studies consisted in establishing the specific effect of the 
saprophytic intestinal flora as a biological normalizer, and in the ability of the 3 microorganism strains to survive at low pH values and under the activity of the gall salts, as well as in establishing the level of the resistance to antibiotics.