Enamel matrix derivative -a new approach in periodontal regeneration

Abstract

Many years goal of the periodontal treatment was to stop the damages produced by the evolution of the inflammatory periodontal disease. In recent years the main aim of the periodontal treatment was to try to regenerate the tissues damaged by the inflammatory periodontal disease. The regeneration of periodontal tissues can be promoted by selecting or stimulating the cells involved in this process. The enamel matrix derivative (EMD) plays an essential role during the development of the tooth; the EMD induces the acellular cementum formation. This stage is a prerequisite in the development of periodontal ligament (i.e. new cementum and new collagen fibers) and alveolar bone. The encouraging results have been obtained by using EMD in conjunction with periodontal surgery for the regeneration of periodontal attachment apparatus lost due to periodontal disease. The purpose of this paper is to review all the histological and clinical data of reports presented until now.