Determination of 2-Thiouracyl in Complex Samples by Liquid Chromatography with Electrochemical Detection

Authors

  • ANTON CIUCU, CRISTIAN CIUCU Author

Keywords:

Amperometric detection, 2-thiouracyl, modified electrode

Abstract

An assay procedure utilizing liquid chromatography and amperometric detection at a chemically modified electrode (CME) has been developed for the determination of 2-thiouracyl (2 ThU) in complex physiological samples. The electrocatalytic activity of the CME, which consisted of a glassy carbon surface coated with an electropolymerized cobalt phthalocyanine film, permitted optimum response at a potential of +0.75 V vs. Ag/AgCl, with a detection limit of 7 pmol for 2 ThU. 

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Published

2023-06-07

Issue

Vol. 41 No. 6 (2023)

Section

Articles