Optimal Control Strategy of a Biotechnological Process Using a Fuzzy Zonal Model

Abstract

This paper deals with the zonal modelling and the optimal control of the biosynthesis processes that take place inside discontinuous bioreactors. There are used fuzzy techniques in order to obtain a general model, no matter of the bioreactor functioning conditions. Using the fuzzy zonal model an algorithm for determining the batch stopping time so that an optimal cost criterion is met was implemented. The fuzzy zonal model and the optimal algorithm were validated based on the experimental data provided by the Food Industry Institute from Bucharest, regarding the biosynthesis process of alpha-amylase with Bacillus subtilis microorganisms.